Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.34 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 3/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | F7 | P08709 | 2/20 | 0.32 |
| ▸ | F3 | P13726 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044047 | 0.88 | CLCN2 (0.43) | CLCN2HTTBIDBCL2L1MCL1 | |
| SCHEMBL9048247 | 0.84 | GPR52 (0.40) | F2RGPR52KDM4EHSD17B10LMNA | |
| SCHEMBL9046560 | 0.84 | GABRA1 (0.40) | GABRA1GABRB2BIDBCL2L1MCL1 | |
| SCHEMBL9045394 | 0.82 | AKR1B1 (0.39) | HTTTSHR | |
| SCHEMBL9045101 | 0.82 | KMT2A (0.39) | GPR52KDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9045271 | 0.81 | GABRA1 (0.37) | GABRA1GABRB2LTB4RLTB4R2CLCN2 | |
| SCHEMBL8615957 | 0.81 | LMNA (0.41) | HTTGPR52MAPTKDM4ELMNA | |
| SCHEMBL9047469 | 0.81 | CA2 (0.34) | GABRA1GABRB2GPR52LMNAALDH1A1 | |
| SCHEMBL10499032 | 0.80 | GABRA1 (0.48) | GABRA1GABRB2CLCN2HTTF2R | |
| SCHEMBL9057953 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |