Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059359 | 0.92 | HPGD (0.48) | LMNAALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9060603 | 0.90 | ALDH1A1 (0.47) | LMNAALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9424244 | 0.84 | ALDH1A1 (0.64) | LMNAALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9059533 | 0.77 | L3MBTL1 (0.47) | LMNAALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9423924 | 0.75 | SCN9A (0.48) | LMNAALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL14385666 | 0.75 | EPHX1 (0.69) | LMNAALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9060928 | 0.74 | ATM (0.39) | LMNAALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9424029 | 0.74 | LMNA (0.52) | LMNAALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9059454 | 0.73 | ALDH1A1 (0.49) | LMNAALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9424343 | 0.73 | ALDH1A1 (0.56) | LMNAALDH1A1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |