Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059533 | 0.86 | L3MBTL1 (0.47) | ATMKMT2AALOX12LMNAGAA | |
| SCHEMBL9059359 | 0.84 | HPGD (0.48) | KMT2ALMNAGAAMAPTALDH1A1 | |
| SCHEMBL5450399 | 0.75 | LMNA (0.58) | ATMKMT2AALOX12LMNAGAA | |
| SCHEMBL9059344 | 0.74 | LMNA (0.46) | KMT2AALOX12LMNAGAAMAPT | |
| SCHEMBL9423957 | 0.70 | L3MBTL1 (0.48) | ATMKMT2AALOX12LMNAGAA | |
| SCHEMBL3436360 | 0.70 | ADRB1 (0.60) | ATMKMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9059862 | 0.70 | POLB (0.37) | KMT2ALMNAGAAMAPTL3MBTL1 | |
| SCHEMBL9060603 | 0.69 | ALDH1A1 (0.47) | KMT2ALMNAGAAMAPTALDH1A1 | |
| SCHEMBL9423924 | 0.69 | SCN9A (0.48) | KMT2ALMNAGAAMAPTALDH1A1 | |
| SCHEMBL9060925 | 0.68 | ALDH1A1 (0.38) | ATMKMT2ALMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |