Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060928 | 0.86 | ATM (0.39) | L3MBTL1MAPTNPSR1ALOX12KMT2A | |
| SCHEMBL9059359 | 0.86 | HPGD (0.48) | MAPTNPSR1KMT2AALDH1A1LMNA | |
| SCHEMBL9423957 | 0.84 | L3MBTL1 (0.48) | L3MBTL1MAPTNPSR1ALOX12KMT2A | |
| SCHEMBL9059228 | 0.78 | MAPT (0.48) | L3MBTL1MAPTNPSR1KMT2AMAPK1 | |
| SCHEMBL5450399 | 0.78 | LMNA (0.58) | L3MBTL1MAPTALOX12KMT2AALDH1A1 | |
| SCHEMBL9059344 | 0.77 | LMNA (0.46) | L3MBTL1MAPTNPSR1ALOX12KMT2A | |
| Iodide SCHEMBL9424070 | 0.76 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1KMT2AMAPK1 | |
| SCHEMBL9060599 | 0.76 | DRD2 (0.48) | L3MBTL1MAPTNPSR1KMT2AMAPK1 | |
| SCHEMBL9423926 | 0.76 | GAA (0.64) | L3MBTL1MAPTNPSR1KMT2AMAPK1 | |
| SCHEMBL12004117 | 0.75 | L3MBTL1 (0.47) | L3MBTL1MAPTNPSR1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |