Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | LGMN | Q99538 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31248708 | 0.90 | LGMN (0.51) | MAPTGAALGMNSMN1; SMN2ALDH1A1 | |
| SCHEMBL904453 | 0.90 | LGMN (0.51) | MAPTGAALGMNSMN1; SMN2ALDH1A1 | |
| SCHEMBL9059762 | 0.87 | ALDH1A1 (0.59) | MAPTGAALGMNSMN1; SMN2ALDH1A1 | |
| SCHEMBL9059418 | 0.87 | PRKDC (0.49) | MAPTGAALGMNSMN1; SMN2ALDH1A1 | |
| SCHEMBL23122504 | 0.84 | KEAP1 (0.49) | MAPTGAALGMNSMN1; SMN2ALDH1A1 | |
| SCHEMBL9424119 | 0.81 | LMNA (0.62) | MAPTGAALGMNSMN1; SMN2ALDH1A1 | |
| SCHEMBL7781079 | 0.81 | KDM4E (0.49) | MAPTGAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL127620 | 0.81 | KEAP1 (0.64) | MAPTGAALGMNSMN1; SMN2ALDH1A1 | |
| SCHEMBL30443433 | 0.81 | KEAP1 (0.64) | MAPTGAALGMNSMN1; SMN2ALDH1A1 | |
| SCHEMBL4435301 | 0.80 | LGMN (0.50) | MAPTGAALGMNSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |