Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410337 | 0.75 | NPSR1 (0.43) | LMNAPOLB | |
| SCHEMBL9059808 | 0.74 | NLRP3 (0.47) | L3MBTL1LMNAKMT2APOLBNLRP3 | |
| SCHEMBL7051356 | 0.73 | KEAP1 (0.53) | KMT2APOLB | |
| SCHEMBL16796919 | 0.72 | ADAMTS4 (0.34) | L3MBTL1LMNAKMT2APOLB | |
| SCHEMBL157674 | 0.72 | L3MBTL1 (0.40) | L3MBTL1LMNANPC1 | |
| SCHEMBL11234113 | 0.72 | L3MBTL1 (0.63) | L3MBTL1LMNAKMT2APOLBNLRP3 | |
| SCHEMBL8558659 | 0.71 | ALDH1A1 (0.45) | KMT2A | |
| SCHEMBL11427391 | 0.71 | ALDH1A1 (0.51) | L3MBTL1KMT2APOLB | |
| SCHEMBL482661 | 0.71 | CA1 (0.53) | LMNAKMT2A | |
| SCHEMBL4879238 | 0.71 | L3MBTL1 (0.47) | L3MBTL1LMNAKMT2APOLBNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019446-A1 | β-CARBOXY SULFONAMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |