Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15190247 | 0.89 | GABRA1 (0.33) | DHFRGABRA1GABRB2TRPA1ATM | |
| SCHEMBL4503427 | 0.84 | TRPA1 (0.41) | GABRA1GABRB2TRPA1ATMALDH1A1 | |
| SCHEMBL4452500 | 0.84 | SHBG (0.40) | TRPA1ATMP4HBALDH1A1TDP1 | |
| SCHEMBL11590403 | 0.82 | SHBG (0.39) | TRPA1ATMP4HBALDH1A1TDP1 | |
| SCHEMBL31438668 | 0.77 | ALDH1A1 (0.43) | GABRA1GABRB2TRPA1ATMALDH1A1 | |
| SCHEMBL1159985 | 0.77 | ALDH1A1 (0.43) | GABRA1GABRB2TRPA1ATMALDH1A1 | |
| SCHEMBL17758745 | 0.77 | TRPA1 (0.50) | GABRA1GABRB2TRPA1ATMALDH1A1 | |
| SCHEMBL20807053 | 0.76 | RIPK1 (0.39) | GABRA1GABRB2TRPA1ATMALDH1A1 | |
| SCHEMBL9558632 | 0.76 | HSPA5 (0.45) | GABRA1GABRB2TRPA1ATMALDH1A1 | |
| SCHEMBL720140 | 0.75 | ESR1 (0.41) | GABRA1GABRB2TRPA1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5239189-A | — | — | None | — | — | JP | disclosed |
| EP-2746822-B1 | PLASTIC LENS | HOYA CORP (JP) | 2016-01-20 | — | — | EP | disclosed |
| EP-2746822-A1 | PLASTIC LENS | HOYA CORPORATION (JP) | 2014-06-25 | — | — | EP | disclosed |
| US-5589541-A | EXTRUSION GRAFTING WITH STYRENE, PACKAGING MATERIAL | DAINIPPON INK AND CHEMICALS INC. (JP) | 1996-12-31 | — | — | US | disclosed |
| JP-H05239189-A | SEALING EPOXY RESIN MOLDING MATERIAL | MATSUSHITA ELECTRIC WORKS LTD | 1993-09-17 | — | — | JP | disclosed |