Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11590403 | 0.98 | SHBG (0.39) | SHBGCYP3A4HIF1ACYP2D6P4HB | |
| SCHEMBL9065619 | 0.84 | DHFR (0.33) | CYP3A4HIF1AP4HBTRPA1ATM | |
| SCHEMBL7597677 | 0.78 | SHBG (0.42) | SHBGCYP3A4HIF1ACYP2D6TRPA1 | |
| SCHEMBL679143 | 0.78 | TRPA1 (0.48) | SHBGCYP3A4HIF1ACYP2D6TRPA1 | |
| SCHEMBL29597345 | 0.78 | TRPA1 (0.48) | SHBGCYP3A4HIF1ACYP2D6TRPA1 | |
| SCHEMBL6558955 | 0.76 | SHBG (0.41) | SHBGCYP3A4HIF1ACYP2D6TRPA1 | |
| SCHEMBL6469365 | 0.76 | ALDH1A1 (0.50) | SHBGCYP3A4HIF1ACYP2D6TRPA1 | |
| SCHEMBL6935470 | 0.76 | SHBG (0.52) | SHBGCYP3A4HIF1ACYP2D6ALDH1A1 | |
| SCHEMBL22500114 | 0.75 | CA2 (0.41) | SHBGCYP3A4HIF1AALDH1A1TSHR | |
| SCHEMBL15190247 | 0.73 | GABRA1 (0.33) | TRPA1ATMALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531587-B2 | Thermal stabilizer composition for halogen-containing vinyl polymers | ROHM AND HAAS COMPANY (US) | 2009-05-12 | — | — | US | disclosed |
| US-7488433-B2 | Thermal stabilizer compositions for halogen-containing vinyl polymers | ROHM AND HAAS COMPANY (US) | 2009-02-10 | — | — | US | disclosed |
| US-20060079611-A1 | Thermal stabilizer compositions for halogen-containing vinyl polymers | AUSTEN STEVEN C | 2006-04-13 | — | — | US | disclosed |
| US-7025904-B2 | Method for improving adhesion of water-based inks to halogen-containing resin articles | ROHM AND HAAS COMPANY (US) | 2006-04-11 | — | — | US | disclosed |
| US-6743840-B1 | HEAT STABILIZER; ODORLESS; DEGRADATION PRODUCTS OF A BLOCKED MERCAPTAN | ROHM AND HAAS COMPANY | 2004-06-01 | — | — | US | disclosed |
| US-6548707-B1 | Deodorizing; heat and oxidation resistance; stabilizers | ROHM AND HAAS COMPANY | 2003-04-15 | — | — | US | disclosed |
| US-20020086920-A1 | METHOD FOR IMPROVING ADHENSION OF WATER-BASED INKS TO HALOGEN- CONTAINING RESIN ARTICLES | PMC CINCINNATI, INC. | 2002-07-04 | — | — | US | disclosed |
| US-4179432-A | 2-HYDROXYBENZOPHENONE, ORGANOTIN MERCAPTIDE PHOTOSTABILITY | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-RE29523-E | Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds | BORG-WARNER CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |
| US-3959220-A | Polymer additives comprising transition metal complexes with trivalent phosphorous compounds | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1976-05-25 | — | — | US | disclosed |