Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.32 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068278 | 1.00 | ACHE (0.38) | ACHEATMGHSRCASRCA1 | |
| Hydrochloric Acid SCHEMBL8798777 | 0.87 | ACHE (0.39) | ACHEATMCASRCA1CA2 | |
| SCHEMBL8800175 | 0.85 | CTSK (0.40) | ACHEATM | |
| SCHEMBL8799426 | 0.76 | ACHE (0.42) | ACHECASRCA1CA2MMP3 | |
| SCHEMBL8799725 | 0.74 | ACHE (0.37) | ACHECASRKLK7PPARA | |
| SCHEMBL8703654 | 0.70 | MMP1 (0.41) | CA1CA2MMP3OPRM1 | |
| SCHEMBL281995 | 0.69 | NPC1 (0.39) | ACHECA1CA2MMP3KLK7 | |
| Hydrochloric Acid SCHEMBL6245752 | 0.68 | NPC1 (0.39) | ACHECA1CA2MMP3KLK7 | |
| SCHEMBL3740322 | 0.67 | RAB9A (0.38) | ACHECA1CA2MMP3KLK7 | |
| Hydrochloric Acid SCHEMBL8798301 | 0.66 | TRPM8 (0.35) | ATMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790240-A1 | Phenol-derivatives having pharmaceutical activity and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |