Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13488755 | 0.82 | ALDH1A1 (0.33) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL13488775 | 0.82 | ALDH1A1 (0.36) | TSHRALDH1A1MAPK1TDP1TGM2 | |
| SCHEMBL28337636 | 0.82 | TSHR (0.41) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL13488763 | 0.75 | — | — | |
| SCHEMBL18755020 | 0.75 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL2319797 | 0.74 | ZDHHC20 (0.36) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL632263 | 0.73 | TGFBR1 (0.33) | ALDH1A1 | |
| SCHEMBL28344102 | 0.73 | TSHR (0.38) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL5057223 | 0.72 | TSHR (0.45) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL15032912 | 0.72 | TSHR (0.45) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277496-B1 | Dental material containing surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2016-03-30 | — | — | EP | claimed |
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | claimed |
| EP-2277496-B1 | Dental material containing surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2016-03-30 | — | — | EP | disclosed |
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | disclosed |
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | disclosed |
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | disclosed |
| EP-2080503-B1 | Dental materials with surface functional fillers | IVOCLAR VIVADENT AG (LI) | 2011-09-14 | — | — | EP | disclosed |
| EP-2277496-A1 | Dental material containing surface-modified fillers | Ivoclar Vivadent AG (LI) | 2011-01-26 | — | — | EP | disclosed |
| EP-2277496-A1 | Dental material containing surface-modified fillers | Ivoclar Vivadent AG (LI) | 2011-01-26 | — | — | EP | disclosed |
| EP-1716836-B1 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2011-01-19 | — | — | EP | disclosed |
| US-20090186960-A1 | DENTAL MATERIALS WITH SURFACE-FUNCTIONALIZED FILLERS | IVOCLAR VIVADENT AG (LI) | 2009-07-23 | — | — | US | disclosed |
| EP-2080503-A1 | Dental materials with surface functional fillers | Ivoclar Vivadent AG (LI) | 2009-07-22 | — | — | EP | disclosed |
| EP-1716836-A1 | Surface-modified fillers | Ivoclar Vivadent AG (LI) | 2006-11-02 | — | — | EP | disclosed |
| US-20060247329-A1 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186960-A1 | DENTAL MATERIALS WITH SURFACE-FUNCTIONALIZED FILLERS | ITGAM, ITGA5, ITGA1 | TSHR 2112/4885ALDH1A1 1596/4885MAPK1 4153/4885 |
| US-20060247329-A1 | Surface-modified fillers | MSR1, HRH4, OR10J3 | TSHR 1605/4885ALDH1A1 2926/4885MAPK1 4560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.