Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194420 | 0.95 | RXFP1 (0.49) | RXFP1TDP1SRCBLMSMN1; SMN2 | |
| SCHEMBL3193220 | 0.92 | RXFP1 (0.46) | RXFP1TDP1SRCBLMKMT2A | |
| SCHEMBL3197838 | 0.92 | SAE1 (0.48) | RXFP1TDP1SRCBLMKMT2A | |
| SCHEMBL3188455 | 0.90 | RXFP1 (0.53) | RXFP1TDP1BLMKMT2AMEN1 | |
| SCHEMBL3193392 | 0.90 | RXFP1 (0.44) | RXFP1TDP1SRCBLMKMT2A | |
| SCHEMBL3191949 | 0.90 | PKM (0.44) | RXFP1KMT2AMEN1POLBCA1 | |
| SCHEMBL3189167 | 0.90 | RXFP1 (0.51) | RXFP1TDP1SRCBLMKMT2A | |
| SCHEMBL3195794 | 0.89 | RXFP1 (0.54) | RXFP1TDP1BLMKMT2AMEN1 | |
| SCHEMBL3187581 | 0.86 | RXFP1 (0.49) | RXFP1TDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3199696 | 0.84 | RXFP1 (0.50) | RXFP1TDP1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100024683-A1 | PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2010-02-04 | — | — | US | claimed |
| EP-2058318-A1 | PHOSPHATE ESTER COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL, AND DENTAL COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2009-05-13 | — | — | EP | claimed |
| EP-2277496-B1 | Dental material containing surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2016-03-30 | — | — | EP | disclosed |
| CN-101516896-B | Phosphate ester compound, metal salt thereof, dental material, and demtal composition | MITSU CHEMICALS INC | 2013-06-05 | — | — | CN | disclosed |
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | disclosed |
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | disclosed |
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | disclosed |
| EP-2058318-B1 | PHOSPHATE ESTER COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL, AND DENTAL COMPOSITION | MITSUI CHEMICALS INC (JP) | 2012-05-16 | — | — | EP | disclosed |
| EP-2058318-B1 | PHOSPHATE ESTER COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL, AND DENTAL COMPOSITION | MITSUI CHEMICALS INC (JP) | 2012-05-16 | — | — | EP | disclosed |
| EP-2080503-B1 | Dental materials with surface functional fillers | IVOCLAR VIVADENT AG (LI) | 2011-09-14 | — | — | EP | disclosed |
| EP-2277496-A1 | Dental material containing surface-modified fillers | Ivoclar Vivadent AG (LI) | 2011-01-26 | — | — | EP | disclosed |
| US-20100024683-A1 | PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20100024683-A1 | PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2010-02-04 | — | — | US | disclosed |
| CN-101516896-A | Phosphate ester compound, metal salt thereof, dental material, and demtal composition | MITSUI CHEMICALS INC (JP) | 2009-08-26 | — | — | CN | disclosed |
| US-20090186960-A1 | DENTAL MATERIALS WITH SURFACE-FUNCTIONALIZED FILLERS | IVOCLAR VIVADENT AG (LI) | 2009-07-23 | — | — | US | disclosed |
| EP-2080503-A1 | Dental materials with surface functional fillers | Ivoclar Vivadent AG (LI) | 2009-07-22 | — | — | EP | disclosed |
| EP-2058318-A1 | PHOSPHATE ESTER COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL, AND DENTAL COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2009-05-13 | — | — | EP | disclosed |
| EP-2058318-A1 | PHOSPHATE ESTER COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL, AND DENTAL COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2009-05-13 | — | — | EP | disclosed |
| EP-1716836-A1 | Surface-modified fillers | Ivoclar Vivadent AG (LI) | 2006-11-02 | — | — | EP | disclosed |
| US-20060247329-A1 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100024683-A1 | PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION | CAD, PPIP5K2, SLC20A1 | RXFP1 4811/4885TDP1 4028/4885SRC 1448/4885 |
| US-20090186960-A1 | DENTAL MATERIALS WITH SURFACE-FUNCTIONALIZED FILLERS | ITGAM, ITGA5, ITGA1 | RXFP1 1296/4885TDP1 4424/4885SRC 3178/4885 |
| US-20060247329-A1 | Surface-modified fillers | MSR1, HRH4, OR10J3 | RXFP1 794/4885TDP1 4617/4885SRC 3571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.