SCHEMBL9070685

SCHEMBL9070685

CNC(=O)Nc1nc(=O)cc(C)[nH]1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ POLB P06746 2/20 0.36
▸ ALDH1A1 P00352 4/20 0.35
▸ RECQL P46063 1/20 0.35
▸ ABL1 P00519 3/20 0.34
▸ GDA Q9Y2T3 1/20 0.34
▸ ADORA3 P0DMS8 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ LCK P06239 1/20 0.33
▸ FGFR1 P11362 1/20 0.33
▸ FGFR2 P21802 1/20 0.33
▸ FGFR3 P22607 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ MEN1 O00255 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27047910 0.84 ABL1 (0.39) SMN1; SMN2POLBALDH1A1ABL1MAPT
SCHEMBL12374457 0.84 ABL1 (0.40) SMN1; SMN2POLBABL1MAPTGAA
SCHEMBL12374464 0.84 TUBB4A (0.33) ALDH1A1ABL1GDAMAPTFGFR1
SCHEMBL13287240 0.83 KDM4E (0.47) POLBALDH1A1GDAADORA3FGFR1
SCHEMBL13051269 0.83 GAA (0.38) ALDH1A1ABL1GDAMAPTKDM4E
SCHEMBL21216730 0.83 ABL1 (0.51) ABL1
SCHEMBL21122922 0.83 KDM4E (0.39) SMN1; SMN2ALDH1A1MAPTLCKFGFR1
SCHEMBL11988255 0.81 TUBB4A (0.35) POLBALDH1A1ABL1GDAKDM4E
SCHEMBL12462229 0.81 CYP3A4 (0.45) POLBALDH1A1GDAMAPTKDM4E
SCHEMBL20806159 0.80 RAB9A (0.41) SMN1; SMN2ABL1MAPTMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024487-A1 SELF-REPAIRING BIOMIMETIC LUBRICANTS AND METHODS OF MAKING AND USING SAME DUKE UNIVERSITY 2024-01-25 — — US disclosed
WO-2022099059-A1 SELF-REPAIRING BIOMIMETIC LUBRICANTS AND METHODS OF MAKING AND USING SAME DUKE UNIVERSITY (US) 2022-05-12 — — WO disclosed
US-10813866-B2 Cosmetic composition, cosmetic treatment method, kit, and compound L'OREAL (FR) 2020-10-27 — — US disclosed
EP-2521530-B1 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, KIT, AND COMPOUND OREAL (FR) 2019-06-26 — — EP disclosed
US-20180029905-A1 THERMORESPONSIVE POLYMERS FOR AQUEOUS APPLICATIONS PHILLIPS 66 COMPANY (US) 2018-02-01 — — US disclosed
US-20180030169-A1 THERMORESPONSIVE POLYMERS PHILLIPS 66 COMPANY (US) 2018-02-01 — — US disclosed
US-20170092388-A1 CONDUCTIVE COMPOSITES AND COMPOSITIONS FOR PRODUCING THE SAME, AND PRODUCTION METHODS THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2017-03-30 — — US disclosed
US-9561165-B2 Cosmetic treatment processes and kit L'OREAL (FR) 2017-02-07 — — US disclosed
US-9561165-B2 Cosmetic treatment processes and kit L'OREAL (FR) 2017-02-07 — — US disclosed
US-20160151267-A1 COMPOSITION COMPRISING A WATER-INSOLUBLE SOLID ORGANIC UV-SCREENING AGENT AND A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS L'OREAL (FR) 2016-06-02 — — US disclosed
US-8722025-B2 Cosmetic dermatological composition, cosmetic treatment method, and hyaluronic acid derivative L'OREAL (FR) 2014-05-13 — — US disclosed
EP-2521738-B1 COSMETIC OR DERMATOLOGICAL COMPOSITION, COSMETIC TREATMENT METHOD, AND HYALURONIC ACID DERIVATIVE OREAL (FR) 2013-10-30 — — EP disclosed
US-20130017164-A1 COSMETIC DERMATOLOGICAL COMPOSITION, COSMETIC TREATMENT METHOD, AND HYALURONIC ACID DERIVATIVE L'OREAL (FR) 2013-01-17 — — US disclosed
US-20130017164-A1 COSMETIC DERMATOLOGICAL COMPOSITION, COSMETIC TREATMENT METHOD, AND HYALURONIC ACID DERIVATIVE L'OREAL (FR) 2013-01-17 — — US disclosed
WO-2013004982-A2 COSMETIC TREATMENT PROCESSES AND KIT L'OREAL (FR) 2013-01-10 — — WO disclosed
WO-2012068573-A2 ADHESIVE COMPOSITIONS AND USE THEREOF HENKEL CORPORATION (US) 2012-05-24 — — WO disclosed
WO-2011083243-A1 COSMETIC TREATMENT METHODS AND KIT L'OREAL (FR) 2011-07-14 — — WO disclosed
WO-2011080450-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION, COSMETIC TREATMENT METHOD, AND HYALURONIC ACID DERIVATIVE L'OREAL (FR) 2011-07-07 — — WO disclosed
US-7459014-B2 Radiation curable inks containing curable gelator additives XEROX CORPORATION (US) 2008-12-02 — — US disclosed
US-7459014-B2 Radiation curable inks containing curable gelator additives XEROX CORPORATION (US) 2008-12-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160151267-A1 COMPOSITION COMPRISING A WATER-INSOLUBLE SOLID ORGANIC UV-SCREENING AGENT AND A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS F2, F12, C1S SMN1; SMN2 3219/4885POLB 64/4885ALDH1A1 1323/4885
US-20240024487-A1 SELF-REPAIRING BIOMIMETIC LUBRICANTS AND METHODS OF MAKING AND USING SAME MUC1, OGG1, DSG1 SMN1; SMN2 3206/4885POLB 501/4885ALDH1A1 634/4885
US-10813866-B2 Cosmetic composition, cosmetic treatment method, kit, and compound KRT18, KIT, TYR SMN1; SMN2 4560/4885POLB 214/4885ALDH1A1 586/4885
US-20130017164-A1 COSMETIC DERMATOLOGICAL COMPOSITION, COSMETIC TREATMENT METHOD, AND HYALURONIC ACID DERIVATIVE CD44, CUTA, NISCH SMN1; SMN2 4547/4885POLB 1922/4885ALDH1A1 291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback