Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ACP1 | P24666 | 2/20 | 0.49 |
| ▸ | GLS | O94925 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5875678 | 0.83 | CYP1A2 (0.62) | HSPA5LMNAFFAR2XBP1CYP1A2 | |
| SCHEMBL7873351 | 0.83 | FFAR2 (0.60) | HSPA5LMNAFFAR2XBP1TSHR | |
| SCHEMBL27228868 | 0.83 | FFAR2 (0.60) | HSPA5LMNAFFAR2XBP1TSHR | |
| SCHEMBL7876854 | 0.82 | SMN1; SMN2 (0.50) | HSPA5LMNAFFAR2NPC1RAB9A | |
| SCHEMBL7868150 | 0.81 | ALDH1A1 (0.51) | HSPA5LMNAFFAR2XBP1CYP1A2 | |
| Serine SCHEMBL8988623 | 0.80 | RAB9A (0.43) | LMNANPC1RAB9ACYP1A2TSHR | |
| SCHEMBL1107000 | 0.80 | ADORA2A (0.68) | HSPA5LMNAFFAR2XBP1TSHR | |
| Bromide SCHEMBL11317007 | 0.79 | LMNA (0.57) | HSPA5LMNAFFAR2XBP1TSHR | |
| SCHEMBL8041336 | 0.78 | CYP2C19 (0.40) | CYP2C19GLSSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL2672708 | 0.78 | EPHX2 (0.60) | FFAR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |