Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | S100B | P04271 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28058576 | 0.92 | MEN1 (0.40) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31024203 | 0.88 | CASR (0.38) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28058677 | 0.75 | MEN1 (0.40) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL9770376 | 0.74 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28058663 | 0.73 | CYP2C19 (0.42) | KMT2AMAPK1TSHRGLAHIF1A | |
| Hydrochloric Acid SCHEMBL7195502 | 0.71 | GPR3 (0.41) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL7636872 | 0.68 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7191899 | 0.68 | GPR3 (0.34) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL1735497 | 0.67 | ALDH1A1 (0.74) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL29518420 | 0.67 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709393-A2 | Olefin polymerization catalyst and process for producing olefin polymer | TOSOH CORPORATION (JP) | 1996-05-01 | — | — | EP | disclosed |