Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | S100B | P04271 | 1/20 | 0.37 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9073065 | 0.92 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL7195502 | 0.82 | GPR3 (0.41) | MEN1KMT2AALDH1A1L3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL28058663 | 0.82 | CYP2C19 (0.42) | KMT2AMAPK1BLMTSHRCNR2 | |
| Hydrochloric Acid SCHEMBL28058677 | 0.81 | MEN1 (0.40) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL31024203 | 0.81 | CASR (0.38) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL7191899 | 0.78 | GPR3 (0.34) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| Ethane SCHEMBL8174121 | 0.73 | GPR3 (0.46) | MEN1KMT2APOLBGPR3CYP19A1 | |
| Hydrochloric Acid SCHEMBL540484 | 0.73 | GPR3 (0.44) | MEN1KMT2APOLBGPR3CYP19A1 | |
| Hydrochloric Acid SCHEMBL7200396 | 0.72 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MAPTMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL28058584 | 0.72 | DDB1 (0.38) | MEN1KMT2ADDB1CRBNGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106133042-B | Ultrahigh molecular weight polyethylene stretches microporous membrane | 东曹株式会社 | 2019-11-26 | — | — | CN | disclosed |
| CN-106133042-A | Ultrahigh molecular weight polyethylene stretching micro-porous film | 东曹株式会社 | 2016-11-16 | — | — | CN | disclosed |
| CN-105377909-A | Ultra-high-molecular-weight polyethylene particles and molded body comprising same | TOSOH CORP | 2016-03-02 | — | — | CN | disclosed |