Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 9/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | S100B | P04271 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9073065 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MAPK1L3MBTL1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL28058576 | 0.81 | MEN1 (0.40) | ALDH1A1MAPK1L3MBTL1MEN1MAPT | |
| SCHEMBL10080950 | 0.70 | ALDH1A1 (0.60) | ALDH1A1MAPK1L3MBTL1TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL7200396 | 0.69 | ALDH1A1 (0.40) | ALDH1A1MAPK1L3MBTL1MAPTHSD17B10 | |
| SCHEMBL9770376 | 0.68 | ALDH1A1 (0.45) | ALDH1A1MAPK1L3MBTL1MEN1MAPT | |
| SCHEMBL10053135 | 0.68 | ALDH1A1 (0.55) | CASRALDH1A1MAPK1L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL28058677 | 0.66 | MEN1 (0.40) | ALDH1A1MAPK1L3MBTL1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL7191899 | 0.66 | GPR3 (0.34) | ALDH1A1MAPK1L3MBTL1MEN1MAPT | |
| SCHEMBL18503025 | 0.65 | CRHR1 (0.43) | CASRCYP3A4HSP90AA1HSP90AB1CRHR1 | |
| SCHEMBL3825308 | 0.64 | LMNA (0.41) | ALDH1A1L3MBTL1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024185503-A1 | RESIN MODIFIER AND RESIN COMPOSITION COMPRISING SAME | 東ソー株式会社 | 2024-09-12 | — | — | WO | disclosed |