Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213202 | 0.92 | ALDH1A1 (0.40) | ACHEALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL11213578 | 0.84 | ACHE (0.44) | TAAR1ACHESTAT3ESR1ESR2 | |
| SCHEMBL9079639 | 0.83 | ACHE (0.39) | ACHESTAT3GRIA4CYP19A1 | |
| SCHEMBL8505708 | 0.81 | AOC3 (0.42) | TAAR1 | |
| SCHEMBL11207430 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2A6TAAR1ACHEMEN1 | |
| SCHEMBL8504349 | 0.80 | MEN1 (0.42) | CYP1A2TAAR1MEN1KMT2ACNR2 | |
| SCHEMBL5494536 | 0.76 | ACHE (0.44) | ACHESTAT3ESR1ESR2GRIA4 | |
| SCHEMBL9078974 | 0.73 | L3MBTL1 (0.42) | CYP1A2ESR1ESR2ALDH1A1HPGD | |
| SCHEMBL11216125 | 0.73 | LMNA (0.48) | CYP1A2CYP2A6TAAR1ALDH1A1KMT2A | |
| SCHEMBL6547394 | 0.72 | CYP1A2 (0.46) | CYP1A2CYP2A6TAAR1ACHESTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269993-A | Diaralkyldichlorosilanes | CHISSO CORPORATION (JP) | 1981-05-26 | — | — | US | disclosed |