Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11839524 | 0.84 | ESR1 (0.38) | L3MBTL1TSHRMAPK1ATMTDP1 | |
| SCHEMBL5490217 | 0.81 | IDO1 (0.38) | ESR1ESR2TP53HPGDNPC1 | |
| SCHEMBL9078974 | 0.80 | L3MBTL1 (0.42) | L3MBTL1TSHRMAPK1ATMTDP1 | |
| SCHEMBL5494536 | 0.79 | ACHE (0.44) | TSHRTDP1ESR1ESR2ALDH1A1 | |
| SCHEMBL5484319 | 0.79 | ADRB2 (0.46) | TSHRMAPK1TDP1TP53LMNA | |
| SCHEMBL5487989 | 0.78 | PYCR1 (0.37) | MAPK1ALDH1A1CYP2A6CYP1A2SMN1; SMN2 | |
| SCHEMBL5489949 | 0.78 | AOC3 (0.35) | ALDH1A1CYP17A1 | |
| SCHEMBL5413664 | 0.77 | TAAR1 (0.52) | TSHRTAAR1ALDH1A1 | |
| SCHEMBL9348164 | 0.76 | TSHR (0.52) | L3MBTL1TSHRMAPK1ATMTDP1 | |
| SCHEMBL18295687 | 0.76 | TSHR (0.52) | L3MBTL1TSHRMAPK1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |