Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359406 | 0.88 | MMP1 (0.49) | L3MBTL1 | |
| SCHEMBL7363926 | 0.86 | L3MBTL1 (0.47) | L3MBTL1 | |
| SCHEMBL7361188 | 0.86 | BACE1 (0.45) | L3MBTL1CTSLCTSSCTSKCTSB | |
| SCHEMBL7356396 | 0.85 | CAPN1 (0.53) | FPR2CAPN1 | |
| SCHEMBL7355409 | 0.85 | CTSL (0.43) | L3MBTL1CTSLCTSSCTSKCTSB | |
| SCHEMBL7354485 | 0.85 | CTSS (0.43) | L3MBTL1CTSLCTSSCTSKCTSB | |
| SCHEMBL9088985 | 0.84 | CAPN1 (0.57) | L3MBTL1CTSLCTSSCTSKCTSB | |
| SCHEMBL7362797 | 0.84 | SRC (0.47) | L3MBTL1 | |
| SCHEMBL7359283 | 0.84 | CAPN9 (0.49) | L3MBTL1CTSLCTSBCAPN1 | |
| SCHEMBL7354780 | 0.84 | LMNA (0.49) | L3MBTL1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |