Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204576 | 0.81 | PTGS2 (0.59) | PTGS2PTGS1CHRNA7AOC3ALOX5 | |
| SCHEMBL9200880 | 0.81 | PTGS2 (0.63) | PTGS2PTGS1CHRNA7CA12CA1 | |
| SCHEMBL7467786 | 0.81 | PTGS2 (0.70) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL9199556 | 0.80 | AOC3 (0.65) | PTGS2PTGS1CHRNA7AOC3 | |
| SCHEMBL7465512 | 0.80 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL7466367 | 0.80 | PTGS2 (0.55) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL9209551 | 0.80 | ALOX5 (0.60) | PTGS2CHRNA7CA9ALOX5 | |
| SCHEMBL8925594 | 0.79 | RARG (0.60) | PTGS2CHRNA7AOC3ALOX5SMN1; SMN2 | |
| SCHEMBL8925566 | 0.79 | CHRNA7 (0.57) | PTGS2CHRNA7AOC3ALOX5SMN1; SMN2 | |
| SCHEMBL9208261 | 0.79 | CHRNA7 (0.51) | PTGS2CHRNA7AOC3ALOX5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550147-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTITHROMBOTIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0554829-A2 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |