SCHEMBL3246072

SCHEMBL3246072

O=[C]c1ccc([C]=O)c(O)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CXCR1 P25024 1/20 0.31
CXCR2 P25025 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL910546 0.80 APP (0.43)
SCHEMBL910590 0.78 CES2 (0.44)
SCHEMBL7171797 0.77
SCHEMBL8333206 0.74 HSD17B10 (0.50)
SCHEMBL7149064 0.74 ALOX15 (0.50)
SCHEMBL3718633 0.74 ALDH1A1 (0.47)
SCHEMBL6364905 0.74 TRPA1 (0.52)
SCHEMBL11092340 0.74 HSD17B10 (0.50)
SCHEMBL7740400 0.71
SCHEMBL102884 0.71 TRPV4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197757-B1 ADMINISTERING ENCAPSULATED, CROSSLINKED DRUG, COSMETIC OR FOOD BASF BEAUTY CARE SOLUTIONS FRANCE SAS (FR) 2001-03-06 US claimed
EP-0357280-A2 Soil release agents having allylderived sulfonated end caps THE PROCTER & GAMBLE COMPANY (US) 1990-03-07 EP claimed
EP-1170318-B2 Melt processible polyether ether ketone polymer SOLVAY SPECIALITIES INDIA PRIV (IN) 2010-07-28 EP disclosed
EP-1170318-B1 Melt processible polyether ether ketone polymer GHARDA CHEMICALS LTD (IN) 2004-07-21 EP disclosed
US-4159336-A ANTIALLERGENS THE UPJOHN COMPANY (US) 1979-06-26 US disclosed
US-4069332-A 5,5'-PHENYLENEBIS(1,2,4-OXADIAZOLE-3-CARBOXYLIC ACIDS OR ESTERS) THE UPJOHN COMPANY (US) 1978-01-17 US disclosed