Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112543 | 0.81 | L3MBTL1 (0.38) | TSHRKMT2AHSD17B10NLRP3KDM4E | |
| SCHEMBL9112803 | 0.70 | ALDH1A1 (0.46) | TSHRKMT2AHSD17B10CYP3A4CYP2D6 | |
| SCHEMBL9112483 | 0.69 | MGAM (0.36) | TSHRKMT2AGAAHSD17B10KDM4E | |
| SCHEMBL9110877 | 0.65 | LMNA (0.57) | TSHRKMT2AHSD17B10CYP3A4CYP2D6 | |
| SCHEMBL6005586 | 0.62 | LTA4H (0.53) | KMT2AMMP8CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL21641193 | 0.62 | CACNA2D1 (0.50) | TSHRKMT2AGAA | |
| SCHEMBL7178642 | 0.61 | ALDH1A1 (0.55) | TSHRKMT2AMMP8MEN1 | |
| SCHEMBL6432556 | 0.61 | CYP2D6 (0.53) | TSHRKMT2AMMP8GAACYP3A4 | |
| SCHEMBL5728738 | 0.61 | KMT2A (0.64) | TSHRKMT2AMMP8GAACYP2D6 | |
| SCHEMBL21157388 | 0.60 | OPRD1 (0.48) | TSHRKMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453509-A | Functionalization of acyl pyridinium salts | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1995-09-26 | — | — | US | disclosed |
| WO-1995010505-A1 | FUNCTIONALIZATION OF ACYL PYRIDINIUM SALTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1995-04-20 | — | — | WO | disclosed |