Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAP2K3 | P46734 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.42 |
| ▸ | NEK10 | Q6ZWH5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233390 | 0.83 | ALDH1A1 (0.67) | MAPTSMN1; SMN2ALDH1A1MEN1NPC1 | |
| SCHEMBL28296154 | 0.75 | ALDH1A1 (0.79) | MAPTSMN1; SMN2ALDH1A1MAP2K3LCK | |
| SCHEMBL43146 | 0.75 | MAPT (0.54) | MAPTSMN1; SMN2ALDH1A1MAP2K3LCK | |
| SCHEMBL4101721 | 0.75 | ALDH1A1 (0.56) | MAPTSMN1; SMN2ALDH1A1MAP2K3LCK | |
| SCHEMBL3574871 | 0.73 | TDP1 (0.54) | MAPTSMN1; SMN2ALDH1A1MAP2K3LCK | |
| SCHEMBL29956691 | 0.72 | MAPT (0.58) | MAPTSMN1; SMN2ALDH1A1MEN1NPC1 | |
| SCHEMBL5101956 | 0.72 | MAPT (0.44) | MAPTSMN1; SMN2ALDH1A1MEN1NPC1 | |
| SCHEMBL28218325 | 0.72 | MAPT (0.58) | MAPTSMN1; SMN2ALDH1A1MEN1NPC1 | |
| SCHEMBL1332157 | 0.70 | MAP2K3 (0.50) | MAPTSMN1; SMN2ALDH1A1MAP2K3LCK | |
| SCHEMBL30643071 | 0.70 | ALDH1A1 (0.53) | MAPTSMN1; SMN2ALDH1A1MAP2K3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |