Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668429 | 0.88 | MAPT (0.48) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL8717639 | 0.84 | KDM4E (0.43) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL14902888 | 0.84 | MAPT (0.43) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL10668944 | 0.83 | KDM4E (0.41) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL5190280 | 0.80 | MAPT (0.51) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL9868108 | 0.76 | KDM4E (0.38) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL2397763 | 0.73 | MAPT (0.54) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL1408653 | 0.73 | KDM4E (0.68) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL2401836 | 0.72 | KDM4E (0.44) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 | |
| SCHEMBL29493000 | 0.72 | MAPT (0.72) | KDM4EMAPTTHRBSMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995010790-A1 | HIGH REFRACTIVE INDEX PHOTOCHROMIC OPHTHALMIC ARTICLE | PPG INDUSTRIES, INC. (US) | 1995-04-20 | — | — | WO | claimed |