Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120308 | 0.87 | TLR7 (0.46) | DHODHTLR7KDM4EABCB11LMNA | |
| SCHEMBL9119796 | 0.82 | DHODH (0.53) | RARBDHODHAGTR1AGTR2TLR7 | |
| SCHEMBL8780486 | 0.76 | NR1H4 (0.39) | LMNAALDH1A1 | |
| SCHEMBL9120742 | 0.75 | RARB (0.46) | RARBAGTR1AGTR2TLR7TDP1 | |
| SCHEMBL7838473 | 0.74 | NR1H4 (0.49) | DHODHAGTR1AGTR2TLR7KDM4E | |
| SCHEMBL7849445 | 0.73 | DHODH (0.51) | RARBDHODHAGTR1AGTR2TLR7 | |
| Hydrochloric Acid SCHEMBL8502040 | 0.73 | NR1H4 (0.48) | DHODHAGTR1AGTR2TLR7KDM4E | |
| SCHEMBL4243783 | 0.71 | DHODH (0.45) | DHODHKDM4ELMNACYP1A2TDP1 | |
| SCHEMBL9118964 | 0.71 | AGTR1 (0.47) | RARBDHODHAGTR1AGTR2TLR7 | |
| SCHEMBL1682210 | 0.71 | LTB4R (0.43) | LMNACYP1A2TDP1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478938-A | Antagonists for angiotensin II receptors; hypotensive, cardiotonic agents; cognitive activators | ROUSSEL UCLAF (FR) | 1995-12-26 | — | — | US | disclosed |
| US-5324839-A | Hypotensive agents, gastrointestinal and urogenital disorders | ROUSSEL-UCLAF (FR) | 1994-06-28 | — | — | US | disclosed |