Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91275 | 0.93 | PPARG (0.38) | ITGB3ITGA2BKDM4ELMNABCHE | |
| SCHEMBL91250 | 0.86 | PARP1 (0.34) | KDM4ELMNA | |
| SCHEMBL91259 | 0.83 | HTR2C (0.33) | KDM4ELMNA | |
| SCHEMBL78724 | 0.83 | KDM4E (0.34) | ITGB3ITGA2BKDM4ELMNAABCB1 | |
| SCHEMBL10289284 | 0.81 | PPARA (0.36) | ITGB3ITGA2BKDM4ELMNAABCB1 | |
| SCHEMBL10289283 | 0.80 | KDM4E (0.33) | ITGB3ITGA2BKDM4ELMNA | |
| SCHEMBL64233 | 0.78 | CHRM5 (0.35) | ITGB3ITGA2BKDM4ELMNAPTGDR2 | |
| SCHEMBL10289281 | 0.77 | FABP4 (0.34) | ITGB3ITGA2BKDM4ELMNAPPARG | |
| SCHEMBL64503 | 0.77 | PPARA (0.33) | ITGB3ITGA2BKDM4ELMNAABCB1 | |
| SCHEMBL78854 | 0.76 | PPARG (0.40) | ITGB3ITGA2BKDM4ELMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |