Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152837 | 0.83 | POLB (0.57) | OPRD1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL9157740 | 0.81 | KMT2A (0.66) | ALDH1A1KMT2AMEN1CA12CA9 | |
| SCHEMBL9152710 | 0.80 | PTGIR (0.43) | ALDH1A1KMT2AMEN1HPGDMAPK1 | |
| SCHEMBL8860030 | 0.80 | CA12 (0.60) | OPRD1ALDH1A1KMT2AMEN1CA12 | |
| SCHEMBL9154021 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1CA12CA9 | |
| SCHEMBL9159771 | 0.77 | CA12 (0.57) | OPRD1ALDH1A1KMT2AMEN1CA12 | |
| SCHEMBL9157966 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1RAB9AKDM4E | |
| SCHEMBL9158437 | 0.76 | HPGD (0.53) | ALDH1A1TSHRKMT2AMEN1MAPT | |
| SCHEMBL9153787 | 0.76 | KMT2A (0.55) | ALDH1A1KMT2AMEN1RAB9APOLB | |
| SCHEMBL9158495 | 0.76 | ALDH1A1 (0.42) | OPRD1ALDH1A1KMT2AMEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |