Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155537 | 0.84 | OPRM1 (0.36) | OPRD1ATM | |
| SCHEMBL9157008 | 0.84 | RAB9A (0.53) | ALDH1A1HSD17B10OPRD1MEN1KMT2A | |
| SCHEMBL9157351 | 0.80 | L3MBTL1 (0.59) | ALDH1A1HSD17B10OPRD1MEN1KMT2A | |
| SCHEMBL9157344 | 0.80 | L3MBTL1 (0.59) | ALDH1A1HSD17B10OPRD1MEN1KMT2A | |
| SCHEMBL9153694 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HSD17B10OPRD1MEN1KMT2A | |
| SCHEMBL9152570 | 0.78 | HSD17B10 (0.51) | ALDH1A1HSD17B10OPRD1MEN1KMT2A | |
| SCHEMBL9154426 | 0.77 | HSD17B10 (0.71) | ALDH1A1HSD17B10OPRD1MEN1KMT2A | |
| SCHEMBL9154470 | 0.76 | OPRD1 (0.45) | ALDH1A1HSD17B10OPRD1MEN1KMT2A | |
| SCHEMBL9156240 | 0.76 | OPRD1 (0.45) | ALDH1A1HSD17B10OPRD1RAB9APOLB | |
| SCHEMBL9155753 | 0.76 | OPRD1 (0.45) | ALDH1A1HSD17B10OPRD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |