Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202626 | 0.87 | KDM4E (0.57) | MTNR1BMTNR1AKDM4EPOLBCYP1A2 | |
| SCHEMBL203718 | 0.87 | CTNNB1 (0.54) | KDM4EMEN1KMT2ARAB9AHTT | |
| SCHEMBL204355 | 0.84 | L3MBTL1 (0.44) | MTNR1BKDM4EPOLBMEN1KMT2A | |
| SCHEMBL203989 | 0.84 | KDM4E (0.44) | MTNR1BKDM4EPOLBMEN1KMT2A | |
| SCHEMBL203538 | 0.83 | LMNA (0.51) | MTNR1BKDM4EPOLBRAB9AMAPK1 | |
| SCHEMBL7759486 | 0.82 | PTGS1 (0.41) | MTNR1BMTNR1AKDM4EPOLBMEN1 | |
| SCHEMBL204217 | 0.82 | LMNA (0.47) | MTNR1BKDM4EPOLBKMT2ARAB9A | |
| SCHEMBL8603089 | 0.82 | LMNA (0.47) | MTNR1BKDM4EPOLBKMT2ARAB9A | |
| SCHEMBL204209 | 0.82 | PTGS1 (0.41) | MTNR1BMTNR1AKDM4EPOLBMEN1 | |
| SCHEMBL205379 | 0.82 | MEN1 (0.49) | MTNR1BKDM4EPOLBCYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468857-A | Phenylmethoxypropenoic esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-11-21 | — | — | US | disclosed |
| US-5334748-A | A methyl 2-aryl heterofunctional phenoxyphenyl-3-methoxy-propenoate compound; treating the plant diseases | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-02 | — | — | US | disclosed |
| EP-0307103-A2 | Fungicides | ZENECA LIMITED (GB) | 1989-03-15 | — | — | EP | disclosed |