Sugi Predict

Sugi Predict / Compounds / SCHEMBL203989

SCHEMBL203989

SCHEMBL203989

COC(C)=C(C(=O)O)c1ccccc1Oc1cccc(OC(C)C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.44
▸ POLB P06746 1/20 0.44
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ MTNR1B P49286 1/20 0.43
▸ NSD2 O96028 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ RAB9A P51151 1/20 0.41
▸ CTNNB1 P35222 1/20 0.40
▸ HTR1D P28221 1/20 0.40
▸ HTR1B P28222 1/20 0.40
▸ IRAK4 Q9NWZ3 1/20 0.40
▸ ACACB O00763 1/20 0.39
▸ ACACA Q13085 1/20 0.39
▸ TSPO P30536 1/20 0.39
▸ MAPT P10636 2/20 0.39
▸ HTT P42858 1/20 0.39
▸ RXRA P19793 1/20 0.39
▸ RXRB P28702 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203988 0.89 KDM4E (0.44) KDM4EPOLBMEN1KMT2ANSD2
SCHEMBL202626 0.89 KDM4E (0.57) KDM4EPOLBMEN1KMT2AMTNR1B
SCHEMBL203718 0.86 CTNNB1 (0.54) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL204355 0.85 L3MBTL1 (0.44) KDM4EPOLBMEN1KMT2AMTNR1B
SCHEMBL203538 0.84 LMNA (0.51) KDM4EPOLBMTNR1BALDH1A1SMN1; SMN2
SCHEMBL9155384 0.84 SIRT2 (0.47) KDM4EPOLBMEN1KMT2AMTNR1B
SCHEMBL8603089 0.83 LMNA (0.47) KDM4EPOLBKMT2AMTNR1BALDH1A1
SCHEMBL7759486 0.83 PTGS1 (0.41) KDM4EPOLBMEN1KMT2AMTNR1B
SCHEMBL204209 0.83 PTGS1 (0.41) KDM4EPOLBMEN1KMT2AMTNR1B
SCHEMBL204217 0.83 LMNA (0.47) KDM4EPOLBKMT2AMTNR1BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 — — US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 — — US disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 — — US disclosed
EP-2670239-B1 FORMULATION FOR THE ANTIMICROBIAL AND FUNGICIDAL TREATMENT OF POLYMERIC MATERIALS, IN PARTICULAR OF PAINTS AND COATINGS SANITIZED AG (CH) 2015-08-12 — — EP disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 — — US disclosed
US-8871277-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2014-10-28 — — US disclosed
WO-2014102228-A1 FORMULATION FOR THE ANTIMICROBIAL TREATMENT OF POLYMER COMPOSITIONS SANITIZED AG (CH) 2014-07-03 — — WO disclosed
EP-2749167-A1 Formulation for the antimicrobial treatment of polyvinyl chloride compositions Sanitized AG (CH) 2014-07-02 — — EP disclosed
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF AVENTIS AGRICULTURE (FR) 2013-12-05 — — US disclosed
US-20130230575-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME OSMOSE, INC. (US) 2013-09-05 — — US disclosed
WO-1997008140-A1 N-SULFONYLIMINODITHIO COMPOUNDS USEFUL FOR PLANT AND MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1997-03-06 — — WO disclosed
EP-0750542-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AG (DE) 1997-01-02 — — EP disclosed
WO-1996032235-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1996-10-17 — — WO disclosed
WO-1996029314-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1996-09-26 — — WO disclosed
WO-1996025044-A1 S-ARYL CYANIMIDOTHIO COMPOUNDS FOR MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1996-08-22 — — WO disclosed
EP-0726710-A1 STABILISATION OF IODINE COMPOUNDS USING INORGANIC SUPPORTING MATERIALS FOR USE IN MATERIAL PROTECTION BAYER AG (DE) 1996-08-21 — — EP disclosed
WO-1996010915-A1 INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-04-18 — — WO disclosed
WO-1995034204-A1 BACTERICIDE THIADIAZOLIDINONES BAYER AKTIENGESELLSCHAFT (DE) 1995-12-21 — — WO disclosed
WO-1995024997-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-21 — — WO disclosed
WO-1995012315-A1 STABILISATION OF IODINE COMPOUNDS USING INORGANIC SUPPORTING MATERIALS FOR USE IN MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1995-05-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 KDM4E 1828/4885POLB 1822/4885MEN1 2747/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 KDM4E 852/4885POLB 4747/4885MEN1 420/4885
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 KDM4E 3120/4885POLB 4213/4885MEN1 3084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.