Sugi Predict

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SCHEMBL204355

SCHEMBL204355

COC(C)=C(C(=O)O)c1ccccc1Oc1cccc(Oc2ccccc2F)c1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ POLB P06746 1/20 0.44
▸ RAB9A P51151 2/20 0.43
▸ NPC1 O15118 2/20 0.43
▸ MTNR1B P49286 1/20 0.43
▸ GCK P35557 2/20 0.42
▸ NPSR1 Q6W5P4 2/20 0.42
▸ LMNA P02545 1/20 0.42
▸ LPAR1 Q92633 2/20 0.41
▸ LPAR5 Q9H1C0 2/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ CTNNB1 P35222 1/20 0.40
▸ PARP10 Q53GL7 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202626 0.89 KDM4E (0.57) KDM4EPOLBRAB9ANPC1MTNR1B
SCHEMBL204354 0.89 L3MBTL1 (0.44) L3MBTL1TDP1KDM4EPOLBRAB9A
SCHEMBL203718 0.86 CTNNB1 (0.54) L3MBTL1TDP1KDM4ERAB9ANPSR1
SCHEMBL203989 0.85 KDM4E (0.44) KDM4EPOLBRAB9AMTNR1BNPSR1
SCHEMBL203538 0.84 LMNA (0.51) L3MBTL1TDP1KDM4EPOLBRAB9A
SCHEMBL9155384 0.84 SIRT2 (0.47) KDM4EPOLBRAB9ANPC1MTNR1B
SCHEMBL8584984 0.84 GCK (0.45) L3MBTL1TDP1KDM4EGCK
SCHEMBL7758309 0.83 KDR (0.39) NPC1GCKLMNAMEN1KMT2A
SCHEMBL203517 0.83 KDR (0.39) NPC1GCKLMNAMEN1KMT2A
SCHEMBL8603089 0.83 LMNA (0.47) L3MBTL1TDP1KDM4EPOLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 — — US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 — — US disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 — — US disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 — — US disclosed
US-8871277-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2014-10-28 — — US disclosed
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF AVENTIS AGRICULTURE (FR) 2013-12-05 — — US disclosed
US-20130230575-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME OSMOSE, INC. (US) 2013-09-05 — — US disclosed
US-8445519-B2 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof AVENTIS AGRICULTURE (FR) 2013-05-21 — — US disclosed
US-8409627-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2013-04-02 — — US disclosed
US-8088801-B2 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof MERIAL LIMITED (US) 2012-01-03 — — US disclosed
EP-0915885-A1 PYRAZINE DERIVATIVES AND THEIR USE FOR MATERIAL AND PLANT PROTECTION BAYER AG (DE) 1999-05-19 — — EP disclosed
EP-0865436-A1 DITHIAZOLDIOXIDES AND THE USE THEREOF AS MICROBICIDES BAYER AG (DE) 1998-09-23 — — EP disclosed
WO-1998004562-A1 PYRAZINE DERIVATIVES AND THEIR USE FOR MATERIAL AND PLANT PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1998-02-05 — — WO disclosed
WO-1997020830-A1 DITHIAZOLDIOXIDES AND THE USE THEREOF AS MICROBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-06-12 — — WO disclosed
EP-0750542-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AG (DE) 1997-01-02 — — EP disclosed
EP-0713485-A1 THIOCARBAMOYL COMPOUNDS BAYER AG (DE) 1996-05-29 — — EP disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 — — EP disclosed
WO-1995024997-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-21 — — WO disclosed
WO-1995004722-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1995-02-16 — — WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 L3MBTL1 1835/4885TDP1 916/4885KDM4E 1828/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 L3MBTL1 1661/4885TDP1 1162/4885KDM4E 852/4885
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 L3MBTL1 1034/4885TDP1 3985/4885KDM4E 3120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.