Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9162155 | 0.91 | CCKBR (0.44) | ALDH1A1MAPTCCKBRHTTEPHX2 | |
| SCHEMBL9162161 | 0.91 | CCKBR (0.44) | ALDH1A1MAPTCCKBRHTTEPHX2 | |
| SCHEMBL9158371 | 0.86 | RAB9A (0.51) | ALDH1A1CCKBREPHX2MEN1RAB9A | |
| SCHEMBL9471547 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CCKBREPHX2MEN1RAB9A | |
| SCHEMBL9159792 | 0.82 | EPHX2 (0.50) | LMNACCKBREPHX2MEN1KMT2A | |
| SCHEMBL9158694 | 0.80 | KMT2A (0.41) | ALDH1A1MAPTCCKBREPHX2MEN1 | |
| SCHEMBL9155538 | 0.80 | ALDH1A1 (0.42) | ALDH1A1CCKBREPHX2MEN1NPC1 | |
| SCHEMBL9156611 | 0.79 | ALDH1A1 (0.45) | ALDH1A1GAATSHREPHX2 | |
| SCHEMBL9156593 | 0.79 | HPGD (0.57) | HPGDKDM4ELMNAALDH1A1GAA | |
| SCHEMBL9159409 | 0.79 | EPHX2 (0.42) | LMNAALDH1A1TSHREPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |