Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157740 | 0.84 | KMT2A (0.66) | SMN1; SMN2LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL9157966 | 0.82 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL9158378 | 0.82 | RAB9A (0.57) | SMN1; SMN2LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL9153787 | 0.81 | KMT2A (0.55) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL9152136 | 0.81 | BCHE (0.54) | SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL9159221 | 0.78 | MEN1 (0.52) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL9158437 | 0.75 | HPGD (0.53) | LMNAALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL8860030 | 0.74 | CA12 (0.60) | ALDH1A1NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL9153829 | 0.73 | OPRD1 (0.46) | LMNAALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL9157052 | 0.73 | NPC1 (0.60) | LMNAALDH1A1NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |