Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445703 | 0.87 | RAPGEF4 (0.65) | RAPGEF4SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL1921159 | 0.87 | RAPGEF4 (0.65) | RAPGEF4SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL30146931 | 0.85 | RAPGEF4 (0.63) | RAPGEF4SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL5667044 | 0.85 | RAPGEF4 (0.63) | RAPGEF4SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL5028501 | 0.83 | RAPGEF4 (0.61) | RAPGEF4SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL30505580 | 0.81 | FGFR2 (0.43) | GAAALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL1921480 | 0.81 | RAPGEF4 (0.59) | RAPGEF4SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL15478852 | 0.79 | RAPGEF4 (0.57) | RAPGEF4SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL916183 | 0.78 | HPGD (0.56) | RAPGEF4SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL21037121 | 0.78 | RAPGEF4 (0.55) | RAPGEF4SMN1; SMN2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647754-B2 | Aromatic diamine derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| US-20110006289-A1 | AROMATIC DIAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110006289-A1 | AROMATIC DIAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | AOC1, DDC, CCNL2 | RAPGEF4 3953/4885SMN1; SMN2 2332/4885MEN1 1230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.