SCHEMBL916183

SCHEMBL916183

Cc1ccc(Nc2ccc([Si](C)(C)C)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.56
GAA P10253 6/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
G6PD P11413 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
RAPGEF4 Q8WZA2 1/20 0.45
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HAO1 Q9UJM8 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPK1 P28482 1/20 0.42
KDM1A O60341 1/20 0.41
MAPT P10636 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2270398 0.90 ALDH1A1 (0.43) HPGDGAAMEN1KMT2AG6PD
SCHEMBL987122 0.84 ACHE (0.53) HPGDRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL50079 0.82 HPGD (0.78) HPGDGAAMEN1KMT2AG6PD
SCHEMBL108881 0.82 HPGD (0.78) HPGDGAAMEN1KMT2AG6PD
SCHEMBL9516537 0.82 HPGD (0.78) HPGDGAAMEN1KMT2AG6PD
SCHEMBL762138 0.81 ALDH1A1 (0.62) HPGDGAAMEN1KMT2AL3MBTL1
SCHEMBL916557 0.80 L3MBTL1 (0.47) HPGDGAAMEN1KMT2AG6PD
SCHEMBL20636767 0.79 KCNH3 (0.43) GAAMEN1KMT2ARAB9ANPC1
Water SCHEMBL8602751 0.79 HPGD (0.74) HPGDGAAMEN1KMT2AG6PD
SCHEMBL916424 0.79 MAPT (0.46) HPGDGAAMEN1KMT2AG6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9865828-B2 Organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-09 US disclosed
US-9276227-B2 Organic light-emitting device and flat panel display including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-03-01 US disclosed
US-9276227-B2 Organic light-emitting device and flat panel display including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-03-01 US disclosed
US-20140175395-A1 ORGANIC LIGHT-EMITTING DEVICE AND FLAT PANEL DISPLAY INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-06-26 US disclosed
US-20140175395-A1 ORGANIC LIGHT-EMITTING DEVICE AND FLAT PANEL DISPLAY INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-06-26 US disclosed
US-20140054559-A1 ORGANIC LIGHT EMITTING DEVICE INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) 2014-02-27 US disclosed
US-20140054559-A1 ORGANIC LIGHT EMITTING DEVICE INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) 2014-02-27 US disclosed
US-8647754-B2 Aromatic diamine derivative and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-02-11 US disclosed
US-20110006289-A1 AROMATIC DIAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2011-01-13 US disclosed
US-20080102311-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080102311-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME L1CAM, EML4, EBPL HPGD 4610/4885GAA 1619/4885MEN1 1200/4885
US-20110006289-A1 AROMATIC DIAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME AOC1, DDC, CCNL2 HPGD 3427/4885GAA 3829/4885MEN1 1230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.