Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 3/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HNF4A | P41235 | 1/20 | 0.34 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160933 | 0.74 | IDH1 (0.37) | IDH1TACR3TACR1PARP11CYP2C9 | |
| SCHEMBL30965432 | 0.69 | HTR1A (0.46) | CALM1 | |
| SCHEMBL8714804 | 0.67 | IDH1 (0.41) | IDH1TACR3TACR1PARP11HNF4A | |
| SCHEMBL27994320 | 0.65 | IDH1 (0.42) | IDH1MPOPARP11HNF4ACALM1 | |
| SCHEMBL9158919 | 0.65 | LIPE (0.42) | THRBLIPERXRARXRBRXRG | |
| SCHEMBL5675962 | 0.65 | PARP11 (0.50) | IDH1TACR3TACR1PARP11CYP2C9 | |
| SCHEMBL27791814 | 0.63 | PARP11 (0.49) | IDH1MPOPARP11CALM1RXRB | |
| SCHEMBL31040985 | 0.61 | PARP11 (0.54) | IDH1PARP11HNF4ACALM1PDK2 | |
| SCHEMBL6901227 | 0.61 | CALM1 (0.50) | IDH1TACR3TACR1MPOPARP11 | |
| SCHEMBL208455 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408760-B1 | NEW HYDROXYLAMINE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0408760-A1 | NEW HYDROXYLAMINE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |