Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165014 | 0.82 | PIM1 (0.49) | PIM1TDO2NOTUMSMN1; SMN2MAPT | |
| SCHEMBL7366347 | 0.81 | PARP1 (0.46) | TDO2SMN1; SMN2MAPTNPSR1ALDH1A1 | |
| SCHEMBL1249841 | 0.81 | AURKA (0.54) | PIM1MAPTPDPK1NPSR1ALDH1A1 | |
| SCHEMBL7370628 | 0.81 | PDE4A (0.52) | TDO2NOTUMSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL1251253 | 0.80 | NPSR1 (0.67) | PIM1SMN1; SMN2MAPTNPSR1ALDH1A1 | |
| SCHEMBL28636871 | 0.79 | PIM1 (0.50) | PIM1TDO2NOTUMSMN1; SMN2MAPT | |
| SCHEMBL7370355 | 0.78 | PDE4A (0.48) | NOTUMALDH1A1LMNAGRM4KDM4E | |
| SCHEMBL1252689 | 0.78 | PARP1 (0.43) | MAPTNPSR1ALDH1A1LMNAPARP1 | |
| SCHEMBL10429345 | 0.77 | TDO2 (0.51) | PIM1TDO2NOTUMNPSR1ALDH1A1 | |
| SCHEMBL7362871 | 0.77 | PDE4D (0.57) | MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | claimed |
| US-5405826-A | Herbicidal pyridopyridazinones and pyridopyridazinethiones | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-04-11 | — | — | US | disclosed |
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | disclosed |