Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | MELK | Q14680 | 1/20 | 0.31 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718 | 0.82 | — | — | |
| SCHEMBL11114659 | 0.80 | — | — | |
| Thiouracil SCHEMBL9172 | 0.80 | — | — | |
| Thiouracil SCHEMBL546068 | 0.80 | — | — | |
| Thiouracil SCHEMBL30091289 | 0.78 | — | — | |
| Thiouracil SCHEMBL27922231 | 0.78 | — | — | |
| SCHEMBL20856861 | 0.77 | ATAD2 (0.39) | TP53DYRK1ABLM | |
| Thiouracil SCHEMBL27970384 | 0.73 | TP53 (0.76) | TP53CRBNMMP2 | |
| Uracil SCHEMBL28120281 | 0.72 | TP53 (0.83) | TP53CRBNMMP2 | |
| Thiouracil SCHEMBL7804101 | 0.71 | TP53 (0.79) | TP53CRBNMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165484-A1 | METHOD FOR OBTAINING DATA USEFUL FOR THE DIAGNOSIS, STRATIFICATION AND/OR FOLLOW-UP OF PATIENTS WITH RHEUMATOID ARTHRITIS | Universidad de Córdoba (ES) | 2020-08-20 | — | — | WO | disclosed |