Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718462 | 0.84 | NPC1 (0.64) | NAMPTRAB9AALDH1A1NPC1 | |
| SCHEMBL27370339 | 0.84 | NPC1 (0.64) | NAMPTRAB9AALDH1A1NPC1 | |
| SCHEMBL2349758 | 0.78 | NAMPT (0.70) | PTPRCPTPN1NAMPTRAB9AALDH1A1 | |
| SCHEMBL6981447 | 0.77 | NPC1 (0.68) | RAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7903033 | 0.76 | RAB9A (0.57) | RAB9AALDH1A1SMN1; SMN2NPC1MET | |
| SCHEMBL839348 | 0.75 | NAMPT (0.66) | PTPRCPTPN1NAMPTRAB9AALDH1A1 | |
| SCHEMBL30847429 | 0.75 | RAB9A (0.61) | PTPN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4716893 | 0.75 | RAB9A (0.61) | PTPN1RAB9ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL14812627 | 0.74 | MAOA (0.41) | RAB9ANPC1MAOAMAOB | |
| SCHEMBL6131245 | 0.74 | MAOA (0.46) | PTPN1ALDH1A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648119-A1 | 5'-INDOLINYL OXAZOLIDINONES USEFUL AGAINST $i(MYCOBACTERIUM TUBERCULOSIS) | THE UPJOHN COMPANY (US) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001110-A1 | 5'-INDOLINYL OXAZOLIDINONES USEFUL AGAINST $i(MYCOBACTERIUM TUBERCULOSIS) | THE UPJOHN COMPANY (US) | 1994-01-20 | — | — | WO | disclosed |