Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177239 | 0.79 | RXRA (0.47) | POLBSMN1; SMN2PKMALDH1A1HPGD | |
| SCHEMBL9179663 | 0.78 | MEN1 (0.49) | KMT2ARAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL11736293 | 0.78 | SMN1; SMN2 (0.40) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL18086910 | 0.75 | OPRM1 (0.37) | HDAC2POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9180083 | 0.75 | NOS1 (0.40) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL9278182 | 0.75 | HDAC3 (0.39) | HDAC2HDAC8HDAC6KMT2ARAB9A | |
| SCHEMBL1315526 | 0.73 | PTPN1 (0.87) | PTPN1CACNA1BAPBA1HDAC2HDAC8 | |
| SCHEMBL4250752 | 0.73 | KCNK9 (0.81) | PTPN1HDAC2HDAC8HDAC6KCNK9 | |
| SCHEMBL9179713 | 0.73 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1128154 | 0.72 | KMT2A (0.78) | PTPN1CACNA1BAPBA1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | claimed |
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | disclosed |