Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177239 | 0.88 | RXRA (0.47) | SMN1; SMN2HPGDCYP26A1RXRARXRB | |
| SCHEMBL9180083 | 0.86 | NOS1 (0.40) | MAPTKMT2AL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL9179713 | 0.83 | ALDH1A1 (0.42) | SMN1; SMN2HPGD | |
| SCHEMBL9179652 | 0.78 | PTPN1 (0.50) | SMN1; SMN2MAPTRAB9AKMT2AHPGD | |
| SCHEMBL9181098 | 0.77 | CA1 (0.41) | SMN1; SMN2MAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9278182 | 0.77 | HDAC3 (0.39) | SMN1; SMN2LMNAMAPTRAB9AKMT2A | |
| SCHEMBL3987895 | 0.76 | TAAR1 (0.35) | — | |
| SCHEMBL5616820 | 0.76 | LMNA (0.43) | SMN1; SMN2LMNAMAPTRAB9AKMT2A | |
| SCHEMBL18086910 | 0.75 | OPRM1 (0.37) | SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL11737844 | 0.74 | NPC1 (0.39) | SMN1; SMN2MAPTRAB9AKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051261-A | HYPOLIPIDEMIC, ANTIDIABETIC | SANDOZ, INC. (US) | 1977-09-27 | — | — | US | disclosed |