Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ATP4A | P20648 | 5/20 | 0.36 |
| ▸ | ATP4B | P51164 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302663 | 0.76 | ATP4A (0.36) | KMT2AMEN1ATP4AATP4BLMNA | |
| SCHEMBL11099962 | 0.69 | ALDH1A1 (0.49) | KMT2AMEN1LMNAMAPK1TSHR | |
| SCHEMBL10989399 | 0.67 | KDM4E (0.50) | KMT2AMEN1LMNACYP1A2CYP2D6 | |
| SCHEMBL11401906 | 0.66 | CASR (0.47) | KMT2AMEN1ATP4AATP4BLMNA | |
| SCHEMBL11166790 | 0.66 | ALDH1A1 (0.49) | KMT2AMEN1ATP4AATP4BLMNA | |
| SCHEMBL2980371 | 0.64 | KDM4E (0.59) | KMT2AMEN1LMNAMAPK1CYP1A2 | |
| Mefenidil SCHEMBL6214486 | 0.64 | PIN1 (0.47) | LMNACYP1A2CYP2C9KDM4EMAPT | |
| SCHEMBL2227911 | 0.64 | PDE10A (0.45) | KMT2AMEN1LMNAABCB1ABCG2 | |
| SCHEMBL30337123 | 0.62 | NLRP3 (0.42) | KMT2AMEN1CYP1A2CYP2C9HDAC6 | |
| SCHEMBL28606764 | 0.62 | NLRP3 (0.42) | KMT2AMEN1CYP1A2CYP2C9HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526975-B1 | Coating composition for optical plastic moldings | ITOH OPTICAL IND (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5322888-A | Curable mixture of hydrolyzable silicate, epoxy-containing silane, dicarboxylic acid or anhydride, and imidazole catalyst; protective coating for optical substrate having a high refractive index; radiation resistance | ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0526975-A2 | Coating composition for optical plastic moldings | ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) | 1993-02-10 | — | — | EP | disclosed |