Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898677 | 0.77 | CSNK2A1 (0.50) | MEN1KMT2AALDH1A1CSNK2A1CYP2C9 | |
| SCHEMBL30135130 | 0.76 | TRPA1 (0.46) | HPGDSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL28471721 | 0.76 | CES2 (0.48) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7597386 | 0.76 | TRPA1 (0.46) | HPGDSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20599448 | 0.74 | RAPGEF4 (0.37) | HPGDNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9328361 | 0.73 | SMN1; SMN2 (0.33) | HPGDNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4399345 | 0.72 | TRPA1 (0.46) | HPGDNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30893091 | 0.72 | TRPA1 (0.46) | HPGDNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL18768788 | 0.72 | SMN1; SMN2 (0.34) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8050752 | 0.71 | POLB (0.46) | HPGDNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | disclosed |