SCHEMBL918522

SCHEMBL918522

[CH2]CSCCSCCSC[CH2]

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4258302 1.00 TDP1 (0.31) TDP1
SCHEMBL918635 0.95
SCHEMBL4254077 0.89
SCHEMBL4253754 0.89
SCHEMBL4256356 0.86
SCHEMBL5107691 0.86
SCHEMBL144770 0.83
SCHEMBL146277 0.83 TDP1 (0.32) TDP1
SCHEMBL143944 0.83 ALDH1A1 (0.34) TDP1
SCHEMBL11849131 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180282046-A1 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2018-10-04 US disclosed
US-20170043931-A1 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2017-02-16 US disclosed
US-9505541-B2 Use of protected N-hydroxyimide derivates and transition metal as oxygen scavenger system in transparent polyolefin films BASF SE (DE) 2016-11-29 US disclosed
EP-1542975-B1 9-CYANO-SUBSTITUTED PERYLENE-3,4-DICARBOXYLIC ACID MONOIMIDES BASF SE (DE) 2016-03-09 EP disclosed
US-20150217923-A1 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2015-08-06 US disclosed
EP-2507307-B1 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2014-02-12 EP disclosed
WO-2011067197-A2 USE OF PROTECTED N-HYDROXYIMIDE DERIVATES AND TRANSITION METAL AS OXYGEN SCAVENGER SYSTEM IN TRANSPARENT POLYOLEFIN FILMS BASF SE (DE) 2011-06-09 WO disclosed
US-20110015295-A1 ADDITIVE MIXTURES FOR AGRICULTURAL ARTICLES GARDI STEFANO 2011-01-20 US disclosed
US-20090286060-A1 Degradable polymer article CIBA CORP. 2009-11-19 US disclosed
US-7550606-B2 9-cyano-substituted perylene-3,4-dicarboxylic acid monoimides BASF AKTIENGESELLSCHAFT (DE) 2009-06-23 US disclosed
US-20050038236-A1 Imidazolidinone derivatives LAZZARI DARIO (IT) 2005-02-17 US disclosed
US-6596461-B1 Useful for stabilizing an organic material against degradation induced by light, heat or oxidation CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-22 US disclosed
US-20030109609-A1 Thioimidazolidine derivatives as light stabilizers for polymers CIBA SPECIALTY CHEMICALS CORP. 2003-06-12 US disclosed
US-20030073835-A1 Light, heat and oxidation resistance; stabilizers CIBA SPECIALTY CHEMICALS CORP. 2003-04-17 US disclosed
EP-1283240-A1 Imidazolidinone derivatives Ciba SC Holding AG (CH) 2003-02-12 EP disclosed
EP-1282605-A2 THIOIMIDAZOLIDINE DERIVATIVES AS LIGHT STABILISERS FOR POLYMERS Ciba SC Holding AG (CH) 2003-02-12 EP disclosed
US-20030027902-A1 Piperazinone derivatives LAZZARI DARIO (IT) 2003-02-06 US disclosed
EP-1133490-A1 PIPERAZINONE DERIVATIVES Ciba SC Holding AG (CH) 2001-09-19 EP disclosed
WO-2001062739-A2 THIOIMIDAZOLIDINE DERIVATIVES AS LIGHT STABILIZERS FOR POLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-30 WO disclosed
WO-2000031069-A1 PIPERAZINONE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015295-A1 ADDITIVE MIXTURES FOR AGRICULTURAL ARTICLES ACMSD, SCD5, DEGS1 TDP1 595/4885
US-20050038236-A1 Imidazolidinone derivatives C9, CBR1, GCN1 TDP1 3596/4885
US-20030073835-A1 Light, heat and oxidation resistance; stabilizers CBR1, CYC1, MT-CO1 TDP1 3297/4885
US-20030109609-A1 Thioimidazolidine derivatives as light stabilizers for polymers CCT4, GCN1, CBR1 TDP1 1527/4885
US-20030027902-A1 Piperazinone derivatives H1-4, EIF4G1, GPX4 TDP1 3756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.