Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pemoline Dione SCHEMBL7864463 | 0.79 | CA2 (1.00) | CA2ALDH1A1RAB9ASLC6A3KMT2A | |
| Pemoline Dione SCHEMBL11265294 | 0.77 | CA2 (0.96) | CA2ALDH1A1RAB9ASLC6A3KMT2A | |
| SCHEMBL28155520 | 0.76 | CA2 (0.67) | CA2ALDH1A1RAB9ASLC6A3KMT2A | |
| SCHEMBL28871521 | 0.71 | CA2 (0.51) | CA2ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL212810 | 0.70 | CA2 (0.50) | CA2ALDH1A1RAB9ASLC6A3KMT2A | |
| SCHEMBL31650964 | 0.68 | ALDH1A1 (0.56) | CA2ALDH1A1RAB9ASLC6A3KMT2A | |
| SCHEMBL983728 | 0.66 | ALDH1A1 (0.54) | CA2ALDH1A1RAB9ASLC6A3KMT2A | |
| SCHEMBL28452557 | 0.66 | ALDH1A1 (0.54) | CA2ALDH1A1RAB9ASLC6A3KMT2A | |
| SCHEMBL16109293 | 0.66 | CA2 (0.53) | CA2ALDH1A1KMT2AMAPTGAA | |
| SCHEMBL4058416 | 0.65 | ALDH1A1 (0.42) | CA2ALDH1A1RAB9ASLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460881-B1 | Process for bicyclic beta-lactams | UNIV NOTRE DAME DU LAC (US) | 1995-11-22 | — | — | EP | disclosed |
| US-5106968-A | Antibiotics | UNIVERSITY OF NOTRE DAME DU LAC COLLEGE OF SCIENCE (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0460881-A1 | Process for bicyclic beta-lactams | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-12-11 | — | — | EP | disclosed |
| US-5051502-A | Process for forming antibiotics | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-09-24 | — | — | US | disclosed |