Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.41 |
| ▸ | ACACB | O00763 | 7/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9478334 | 0.86 | FFAR1 (0.40) | ALOX5PTGS1PTGS2FFAR1PTGES | |
| SCHEMBL9197210 | 0.77 | PTGES (0.58) | ALOX5PTGS1PTGS2FFAR1ACACB | |
| SCHEMBL7344579 | 0.74 | PTGS2 (0.46) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9192422 | 0.74 | FFAR1 (0.58) | ALOX5PTGS1PTGS2FFAR1ACACB | |
| SCHEMBL9190852 | 0.74 | FFAR1 (0.58) | ALOX5PTGS1PTGS2FFAR1ACACB | |
| SCHEMBL9192556 | 0.73 | ALOX5 (0.45) | ALOX5PTGS1PTGS2FFAR1ACACB | |
| SCHEMBL9192563 | 0.72 | PTGES (0.56) | ALOX5PTGS1PTGS2PTGES | |
| SCHEMBL9197154 | 0.72 | PTGES (0.50) | ACACBPTGES | |
| Hydrochloric Acid SCHEMBL7099233 | 0.71 | SLC7A5 (0.51) | PTGS1PTGS2FFAR1ACACBKDM4E | |
| Hydrochloric Acid SCHEMBL7099236 | 0.71 | SLC7A5 (0.51) | PTGS1PTGS2FFAR1ACACBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468281-B1 | Substituted phenylacetylenes, pharmaceuticals containing them and methods for the preparation of these compounds and pharmaceuticals | GRUENENTHAL GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5202349-A | Lipoxygenase inhibitors, antiasthatics | GRUENENTHAL GMBH (DE) | 1993-04-13 | — | — | US | disclosed |
| EP-0468281-A1 | Substituted phenylacetylenes, pharmaceuticals containing them and methods for the preparation of these compounds and pharmaceuticals | Grünenthal GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |