Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036010 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1MTNR1AGAAMAPT | |
| SCHEMBL8960126 | 0.82 | HTT (0.39) | KDM4EALDH1A1MTNR1AMAPTHPGD | |
| SCHEMBL5519173 | 0.81 | L3MBTL1 (0.35) | ALDH1A1MTNR1AGAAMAPTMEN1 | |
| SCHEMBL921795 | 0.80 | HTT (0.50) | HTT | |
| SCHEMBL1135899 | 0.79 | NDUFS8 (0.49) | KDM4EALDH1A1MTNR1AMAPTHPGD | |
| SCHEMBL4114408 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1MTNR1AGAAMAPT | |
| SCHEMBL919396 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1MTNR1AGAAMAPT | |
| SCHEMBL9856070 | 0.78 | MGAM (0.55) | KDM4EALDH1A1MTNR1AGAALMNA | |
| SCHEMBL9727736 | 0.78 | CYP19A1 (0.48) | KDM4EALDH1A1MTNR1AGAAMGAM | |
| SCHEMBL14012896 | 0.78 | MAOB (0.52) | KDM4EALDH1A1MTNR1AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115083-B2 | Compounds from Antrodia cinnamomea and use thereof | SIMPSON BIOTECH CO., LTD. (TW) | 2015-08-25 | — | — | US | claimed |
| US-20140179753-A1 | COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF | SIMPSON BIOTECH CO., LTD. (TW) | 2014-06-26 | — | — | US | claimed |
| US-20130225649-A1 | COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF | SIMPSON BIOTECH CO., LTD. (TW) | 2013-08-29 | — | — | US | claimed |
| US-9115083-B2 | Compounds from Antrodia cinnamomea and use thereof | SIMPSON BIOTECH CO., LTD. (TW) | 2015-08-25 | — | — | US | disclosed |
| US-20140179753-A1 | COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF | SIMPSON BIOTECH CO., LTD. (TW) | 2014-06-26 | — | — | US | disclosed |
| US-8703968-B2 | Compounds from Antrodia cinnamomea and use thereof | SIMPSON BIOTECH CO., LTD. (TW) | 2014-04-22 | — | — | US | disclosed |
| US-20130225649-A1 | COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF | SIMPSON BIOTECH CO., LTD. (TW) | 2013-08-29 | — | — | US | disclosed |
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2345328-A1 | COMPOSITION FOR AGRICULTURAL USE | Sumitomo Chemical Company, Limited (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20110009454-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2248423-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | Sumitomo Chemical Company, Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| EP-1764363-A2 | SUBSTITUTED ACETOPHENONEDERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-03-21 | — | — | EP | disclosed |
| US-6800630-B2 | CYTOSTATIC ACTIVITY, INHIBITORY ACTIVITY AGAINST A SIGNAL DERIVED FROM RAS ONCOGENE PRODUCTS | SHIONOGI & CO., LTD. (JP) | 2004-10-05 | — | — | US | disclosed |
| EP-1251129-B1 | PYRIMIDINE DERIVATIVES HAVING ANTITUMOR EFFECT | SHIONOGI & CO (JP) | 2004-06-09 | — | — | EP | disclosed |
| US-20030203894-A1 | Pyrimidine derivatives having antitumor effect | SHIONOGI & CO., LTD. (JP) | 2003-10-30 | — | — | US | disclosed |
| EP-1251129-A1 | PYRIMIDINE DERIVATIVES HAVING ANTITUMOR EFFECT | SHIONOGI & CO., LTD. (JP) | 2002-10-23 | — | — | EP | disclosed |
| US-6420367-B1 | RAS GENE | SHIONOGO & CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1097933-A1 | PYRIMIDINE DERIVATIVES EXHIBITING ANTITUMOR ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203894-A1 | Pyrimidine derivatives having antitumor effect | TYMS, TYMP, RRM1 | KDM4E 1449/4885ALDH1A1 1562/4885MTNR1A 3257/4885 |
| US-20130225649-A1 | COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF | HAVCR2, CYP51A1, NPC1 | KDM4E 3958/4885ALDH1A1 121/4885MTNR1A 3898/4885 |
| US-20110009454-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | WIZ, TST, NAT1 | KDM4E 3657/4885ALDH1A1 2743/4885MTNR1A 1569/4885 |
| US-20140179753-A1 | COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF | HAVCR2, CYP51A1, NPC1 | KDM4E 3958/4885ALDH1A1 121/4885MTNR1A 3898/4885 |
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | H1-0, H1-3, H1-2 | KDM4E 3733/4885ALDH1A1 4326/4885MTNR1A 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.