Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.96 |
| ▸ | MEN1 | O00255 | 5/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.96 |
| ▸ | HTT | P42858 | 5/20 | 0.96 |
| ▸ | RAB9A | P51151 | 5/20 | 0.96 |
| ▸ | BLM | P54132 | 4/20 | 0.96 |
| ▸ | NPC1 | O15118 | 4/20 | 0.96 |
| ▸ | MAPT | P10636 | 4/20 | 0.96 |
| ▸ | POLB | P06746 | 3/20 | 0.96 |
| ▸ | APAF1 | O14727 | 2/20 | 0.96 |
| ▸ | THRB | P10828 | 2/20 | 0.96 |
| ▸ | PKM | P14618 | 2/20 | 0.96 |
| ▸ | RECQL | P46063 | 2/20 | 0.96 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.96 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.96 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.96 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.96 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.96 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.96 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29362921 | 1.00 | NSD2 (0.98) | NSD2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29349411 | 0.99 | NSD2 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2409472 | 0.99 | NSD2 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL6426499 | 0.99 | NSD2 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL10035965 | 0.99 | NSD2 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Iodide SCHEMBL145357 | 0.98 | MEN1 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Iodide SCHEMBL5500973 | 0.98 | MEN1 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Iodide SCHEMBL145356 | 0.98 | MEN1 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL9015126 | 0.98 | NSD2 (0.98) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Bromide SCHEMBL10431222 | 0.90 | NSD2 (0.80) | NSD2ALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3958991-A | PHOTOCONDUCTOR | EASTMAN KODAK COMPANY (US) | 1976-05-25 | — | — | US | claimed |
| EP-0333435-B1 | High contrast photographic element and emulsion and process for their use | EASTMAN KODAK CO (US) | 1995-12-13 | — | — | EP | disclosed |
| EP-0345025-B1 | High contrast photographic recording material and emulsion and process for their development | EASTMAN KODAK CO (US) | 1994-03-09 | — | — | EP | disclosed |
| US-5126227-A | High speed, low fogging, quality, efficiency | EASTMAN KODAK COMPANY (US) | 1992-06-30 | — | — | US | disclosed |
| US-5104769-A | Negative working silver halide and arylhydrazide nucleating agent | EASTMAN KODAK COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| US-5041355-A | High contrast photographic element including an aryl sulfonamidophenyl hydrazide containing ethyleneoxy groups | EASTMAN KODAK COMPANY (US) | 1991-08-20 | — | — | US | disclosed |
| US-4994365-A | Nucleating agents | EASTMAN KODAK COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| US-4988604-A | Silver halide elements for development with alkaline agent, multilayer, nucleation agent | EASTMAN KODAK COMPANY (US) | 1991-01-29 | — | — | US | disclosed |
| US-4975354-A | Silver halide developed in presence of a hydrazone using an aqueous alkaline solution; black and white photography; lithography | EASTMAN KODAK COMPANY (US) | 1990-12-04 | — | — | US | disclosed |
| EP-0209012-B1 | HIGH CONTRAST PHOTOGRAPHIC ELEMENTS EXHIBITING REDUCED PEPPER FOG | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-11-07 | — | — | EP | disclosed |
| US-4560638-A | Halftone imaging silver halide emulsions, photographic elements, and processes which employ novel arylhydrazides | EASTMAN KODAK COMPANY (US) | 1985-12-24 | — | — | US | disclosed |
| US-4304769-A | PESTICIDES | EASTMAN KODAK COMPANY (US) | 1981-12-08 | — | — | US | disclosed |
| US-4247627-A | Photographic elements having hydrophilic colloid layers containing hydrophobic ultraviolet absorbers uniformly loaded in latex polymer particles | EASTMAN KODAK COMPANY (US) | 1981-01-27 | — | — | US | disclosed |
| US-4214047-A | Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles | EASTMAN KODAK COMPANY (US) | 1980-07-22 | — | — | US | disclosed |
| US-4203716-A | Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles | EASTMAN KODAK COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4199363-A | Processes for achieving uniform, efficient distribution of hydrophobic materials through hydrophilic colloid layers and loaded latex compositions | EASTMAN KODAK COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| US-4097284-A | TRIMETHINECYANINE DYE AND A NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING A MERCAPTO | FUJI PHOTO FILM CO., LTD. (JA) | 1978-06-27 | — | — | US | disclosed |
| US-4004572-A | Solar energy collection and retrieval employing reversible photochemical isomerization | BATTELLE DEVELOPMENT CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |
| US-4004573-A | Process and apparatus for solar energy collection and retrieval | BATTELLE DEVELOPMENT CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |
| US-3979213-A | METHINE DYES | GILMAN JR PAUL B | 1976-09-07 | — | — | US | disclosed |