Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.98 |
| ▸ | MEN1 | O00255 | 5/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.98 |
| ▸ | HTT | P42858 | 5/20 | 0.98 |
| ▸ | RAB9A | P51151 | 5/20 | 0.98 |
| ▸ | BLM | P54132 | 4/20 | 0.98 |
| ▸ | NPC1 | O15118 | 4/20 | 0.98 |
| ▸ | MAPT | P10636 | 4/20 | 0.98 |
| ▸ | POLB | P06746 | 3/20 | 0.98 |
| ▸ | APAF1 | O14727 | 2/20 | 0.98 |
| ▸ | THRB | P10828 | 2/20 | 0.98 |
| ▸ | PKM | P14618 | 2/20 | 0.98 |
| ▸ | RECQL | P46063 | 2/20 | 0.98 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.98 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.98 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.98 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.98 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.98 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29349411 | 1.00 | NSD2 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2409472 | 1.00 | NSD2 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL10035965 | 1.00 | NSD2 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Iodide SCHEMBL145356 | 0.99 | MEN1 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Iodide SCHEMBL145357 | 0.99 | MEN1 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Iodide SCHEMBL5500973 | 0.99 | MEN1 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Bromide SCHEMBL9192803 | 0.99 | NSD2 (0.98) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL9015126 | 0.99 | NSD2 (0.98) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Bromide SCHEMBL29362921 | 0.99 | NSD2 (0.98) | NSD2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL12611407 | 0.91 | NSD2 (0.83) | NSD2ALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263590-B1 | THERMALLY IMAGEABLE ELEMENT AND LITHOGRAPHIC PRINTING PLATE | KODAK POLYCHROME GRAPHICS CO (US) | 2005-03-16 | — | — | EP | claimed |
| WO-2024118805-A1 | TOPOISOMERASE III (TOP3) INHIBITORS AND ANTIVIRAL COMPOUNDS BASED ON CYANINES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-06-06 | — | — | WO | disclosed |
| US-10028936-B2 | Compositions and methods employing Wolbachia FtsZ as a target for Albendazole sulfone | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-07-24 | — | — | US | disclosed |
| US-20180177765-A9 | Compositions and Methods employing Wolbachia FtsZ as a target for Albendazole sulfone | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-06-28 | — | — | US | disclosed |
| US-20180042900-A1 | Compositions and Methods employing Wolbachia FtsZ as a target for Albendazole sulfone | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-15 | — | — | US | disclosed |
| US-20170340622-A1 | METHOD OF DETECTING CANCER STEM CELL, METHOD OF SCREENING CANCER STEM CELL, AND METHOD OF INHIBITING CANCER STEM CELL | CANON KK (JP) | 2017-11-30 | — | — | US | disclosed |
| US-20170340622-A1 | METHOD OF DETECTING CANCER STEM CELL, METHOD OF SCREENING CANCER STEM CELL, AND METHOD OF INHIBITING CANCER STEM CELL | CANON KK (JP) | 2017-11-30 | — | — | US | disclosed |
| US-20150182518-A1 | CANCER CELL INHIBITORY DRUG AND CANCER STEM-CELL DETECTION PROBE | CANON KABUSHIKI KAISHA (JP) | 2015-07-02 | — | — | US | disclosed |
| US-20130219529-A1 | PROBE FOR A HAIR CELL, AND LABELLING METHOD FOR A HAIR CELL USING THE PROBE FOR A HAIR CELL | CANON KABUSHIKI KAISHA (JP) | 2013-08-22 | — | — | US | disclosed |
| US-8460639-B2 | Probe for a hair cell, and labelling method for a hair cell using the probe for a hair cell | CANON KABUSHIKI KAISHA (JP) | 2013-06-11 | — | — | US | disclosed |
| US-20100166663-A1 | PROBE FOR A HAIR CELL, AND LABELLING METHOD FOR A HAIR CELL USING THE PROBE FOR A HAIR CELL | CANON KABUSHIKI KAISHA (JP) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340622-A1 | METHOD OF DETECTING CANCER STEM CELL, METHOD OF SCREENING CANCER STEM CELL, AND METHOD OF INHIBITING CANCER STEM CELL | MKI67, KIT, ALDH1A1 | NSD2 2895/4885ALDH1A1 3/4885MEN1 2213/4885 |
| US-20180177765-A9 | Compositions and Methods employing Wolbachia FtsZ as a target for Albendazole sulfone | WIZ, RAB5IF, ATP5PB | NSD2 3246/4885ALDH1A1 4815/4885MEN1 4787/4885 |
| US-20150182518-A1 | CANCER CELL INHIBITORY DRUG AND CANCER STEM-CELL DETECTION PROBE | MKI67, ABCB1, CD44 | NSD2 3220/4885ALDH1A1 6/4885MEN1 2178/4885 |
| US-20180042900-A1 | Compositions and Methods employing Wolbachia FtsZ as a target for Albendazole sulfone | WIZ, RAB5IF, ATP5PB | NSD2 3246/4885ALDH1A1 4815/4885MEN1 4787/4885 |
| US-10028936-B2 | Compositions and methods employing Wolbachia FtsZ as a target for Albendazole sulfone | WIZ, RAB5IF, ATP5PB | NSD2 3246/4885ALDH1A1 4815/4885MEN1 4787/4885 |
| US-20100166663-A1 | PROBE FOR A HAIR CELL, AND LABELLING METHOD FOR A HAIR CELL USING THE PROBE FOR A HAIR CELL | ALPG, MKI67, KRT18 | NSD2 3647/4885ALDH1A1 167/4885MEN1 2225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.