Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.96 |
| ▸ | MEN1 | O00255 | 5/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.96 |
| ▸ | HTT | P42858 | 5/20 | 0.96 |
| ▸ | RAB9A | P51151 | 5/20 | 0.96 |
| ▸ | BLM | P54132 | 4/20 | 0.96 |
| ▸ | NPC1 | O15118 | 4/20 | 0.96 |
| ▸ | MAPT | P10636 | 4/20 | 0.96 |
| ▸ | POLB | P06746 | 3/20 | 0.96 |
| ▸ | APAF1 | O14727 | 2/20 | 0.96 |
| ▸ | THRB | P10828 | 2/20 | 0.96 |
| ▸ | PKM | P14618 | 2/20 | 0.96 |
| ▸ | RECQL | P46063 | 2/20 | 0.96 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.96 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.96 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.96 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.96 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.96 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.96 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409472 | 0.99 | NSD2 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL6426499 | 0.99 | NSD2 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL10035965 | 0.99 | NSD2 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29349411 | 0.99 | NSD2 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Iodide SCHEMBL5500973 | 0.98 | MEN1 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Bromide SCHEMBL9192803 | 0.98 | NSD2 (0.98) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Iodide SCHEMBL145356 | 0.98 | MEN1 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Iodide SCHEMBL145357 | 0.98 | MEN1 (1.00) | NSD2ALDH1A1MEN1KMT2AHTT | |
| Bromide SCHEMBL29362921 | 0.98 | NSD2 (0.98) | NSD2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL12611407 | 0.90 | NSD2 (0.83) | NSD2ALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508910-B1 | Spectrally sensitized octahedral emulsions with buried shell sensitization | EASTMAN KODAK CO (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5268264-A | Photography | EASTMAN KODAK COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
| EP-0508910-A2 | Spectrally sensitized octahedral emulsions with buried shell sensitization | EASTMAN KODAK COMPANY (US) | 1992-10-14 | — | — | EP | disclosed |